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Ezetimibe: Inhibits absorption of cholesterol at the brush border of the small intestine, leading to a decreased delivery of cholesterol to the liver.
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Studies have shown that Ezetimibe directly binds with Niemann-Pick C1-Like 1 (NPC1L1) protein (a critical mediator of cholesterol absorption) present on the gastrointestinal tract epithelial cells and hepatocytes.
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Another panel member, Milton Packer of Baylor University, said that \"the benefit here is small.
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